13C urea breath test (Helicobacter pylori)
The 13C breath test is a safe and non-invasive test used to detect the presence of Helicobacter pylori (H. pylori) bacteria in the stomach.
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How to prepare
The 13C breath test is a safe and non-invasive test used to detect the presence of Helicobacter pylori (H. pylori) bacteria in the stomach. This bacterium is common in humans and may be associated with inflammation of the stomach lining, the formation of ulcers, and even the development of stomach cancer.
During the test, the patient drinks a solution containing a small amount of 13C-labelled urea. If H. pylori is present in the stomach, the bacteria break down this substance and release carbon dioxide (CO₂), which enters the bloodstream and is then exhaled. Breath samples are analysed to detect the presence of labelled CO₂. If it is detected, the test yields a positive result for H. pylori infection.
The test is quick and convenient, usually taking about 30 minutes, and the patient does not experience any discomfort during the procedure.
How to prepare for the test
- Medication: stop taking antibiotics 4 weeks before the test and proton pump inhibitors (e.g. Nolpaza, Escadra, omeprazole) 2 weeks before the test, as these medicines can affect the accuracy of the result.
- Diet: do not eat or drink anything (except plain water) for 6–8 hours before the test. Avoid alcohol, caffeine and spicy food.
- Other restrictions: do not smoke for at least 6–8 hours before the test.
- Brush your teeth before the test.
- Do not use chewing gum or breath fresheners before the test.
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